Non Species Specific Furkid Topics > Pet Meds

Baytril

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Pookie:
The holistic vet said Pookie would definitely need antibiotics  :'( and suggested Baytril.  She nixed the colloidal silver, saying cats lack an enzyme to handle toxicity from herbs.  I didn't think at the time to say, "It's not an herb, it's a metal."  But at this point, I'm not going to argue.

I see Baytril isn't for dental use, but at this point, I'm thinking it might be the way to go.  It's in a different class, so hopefully he'd be ok on it.  Feel free to add your thoughts/comments/experiences with Baytril here.  The reality is, I can't put off getting his mouth taken care of much longer, so I need to make a decision soon.  I guess I just really want to know if anyone's had a bad experience with it (or their pets, I should say).

Thanks in advance!   :-* :-* HeadButt HeadButt

DeeDee:
Dannyboy had been given Baytril once, and he did well with it. Didn't seem to be any side effects at all. But he was a dog. It's a broad spectrum antibiotic though, so it should go ahead and break up the DNA of most bacteria.

I decided to look it up for cats, and there's only one thing that would concern me.


--- Quote ---SPECIAL CLINICAL CONCERNS
Adverse Effects and Toxicity
Although side effects with the older quinolones (nalidixic and oxolinic acids) were relatively common, the newer ones seem to be well tolerated. However, several adverse effects can limit use in selected species. Retinal degeneration may occur acutely in cats, with the risk greatest for enrofloxacin and least for marbofloxacin. The mechanism is not known. Quinolones tend to be neurotoxic, and convulsions can occur at high doses. Vomiting and diarrhea rarely develop with fluoroquinolones. Dermal reactions and photosensitization have been described in humans, but the occurrence seems low. Hemolytic anemia has also been seen. Administering large doses of quinolones for any length of time during pregnancy has resulted in embryonic loss and maternal toxicity. Because high prolonged dosages in growing dogs have produced cartilaginous erosions leading to permanent lameness, excessive use of quinolones should be avoided in immature animals. Quinolone administration in horses has not yet been extensively studied, but there is some indication that damage to the cartilage in weightbearing joints may be seen. http://www.merckmanuals.com/vet/pharmacology/antibacterial_agents/quinolones.html
--- End quote ---

If you go that route, there's a warning about making sure you wash your hands well after handling it.


--- Quote ---Baytril is not for use by humans, in fact it has properties which make it toxic for humans. After handling Baytril be sure to wash your hands thoroughly. Medication should be kept in a secure place away from children and pets. If accidentally consumed by humans, seek immediate emergency medical help. If you get Baytril in your eyes, immediately flush eyes with water for 15 minutes and seek medical help. http://www.critters360.com/index.php/baytril-side-effects-and-uses-for-dogs-3937/
--- End quote ---

Also, I'm not positive, but I think you cannot use Pepcid when giving this stuff:


--- Quote ---Baytril levels in the body may increase if given with other drugs which are metabolized in the liver. Dosage may need to be adjusted in these cases. Drugs containing certain metals such as calcium, iron, aluminum and magnesium may decrease Baytril’s absorption., requiring larger doses of Baytril. Common drugs Baytril can react with include antacids, sucralfate, theophylline, penicillin, Rimadyl, cephalosporin antibiotics and NSAIDS (non-steroidal anti-inflammatory drugs).
http://www.critters360.com/index.php/baytril-side-effects-and-uses-for-dogs-3937/
--- End quote ---


--- Quote ---Drug Interactions or Contraindications

Concurrent administration of a quinolone, including enrofloxacin, with cation-containing GI products such as magnesium/aluminum antacids or sucralfate, or GI products containing calcium, iron, or zinc may reduce its absorption. It is suggested to separate dosing from any of these products by 2 hours.
Theophylline blood levels may be increased when used with enrofloxacin.

Probenecid blocks tubular secretion of enrofloxacin and may cause an increase in its blood level and half life.

Synergism can occur when aminoglycosides, cephalosporins, and extended-spectrum penicillins are used with fluorinated quinolones such as enrofloxacin. http://ratguide.com/meds/antimicrobial_agents/enrofloxacin_baytril.php
--- End quote ---

Middle Child:
Good info Dee. I think the Baytril would be fine, though he will have to go off the pepcid while he is on it.

Can you pill Quickly?  Baytril is very very bitter.  You've got to get it in and down in a split second to avoid foaming and gagging.

DeeDee:

--- Quote from: Middle Child on October 10, 2014, 04:46:40 PM ---Can you pill Quickly?  Baytril is very very bitter.  You've got to get it in and down in a split second to avoid foaming and gagging.

--- End quote ---

I was wondering about that. Dr's Foster & Smith store said something about pills and otic suspension for ears. Nothing about oral drops.

Middle Child:
No drops.  Baytril comes in tablet form.  It's a little brown pill, supposedly chicken flavored but I never heard of  a cat who thought so. I'm trying to remember the doses Mazy cat and Tolly Angel took. I think it was 1/4 tablet twice a day but I'm not positive. I'll look it up tomorrow.

I find giving pills much easier than liquids, to a cat.

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